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Trihexyphenidyl is an oral anticholinergic agent used predominantly in the symptomatic therapy of Parkinson disease and movement disorders Trihexyphenidyl has not been associated with serum enzyme elevations during treatment but has been implicated in rare cases of acute liver injury Background
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Apr 19 2021Limited information indicates that maternal doses of trihexyphenidyl up to 4 mg daily together with haloperidol did not produce any adverse effects in breastfed infants Long term use of trihexyphenidyl might reduce milk production or milk letdown but a single dose is not likely to interfere with breastfeeding During long term use observe for signs of decreased lactation insatiety
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Trihexyphenidyl THP benzhexol trihex marketed as Artane and others is an antispasmodic drug used to treat stiffness tremors spasms and poor muscle control It is an agent of the antimuscarinic class and is often used in management of Parkinson s was approved by the FDA for the treatment of Parkinson s in the US in It is on the World Health Organization s List of
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DL Trihexyphenidyl hydrochloride has been used to develop a capillary zone electrophoretic method with end column electrochemiluminescence ECL based detection technique Biochem/physiol Actions DL trihexyphenidyl hydrochloride Benzhexol hydrochloride is known to function as an antimuscarinic agent and a centrally acting anticholinergic It
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Jul 22 2022Trihexyphenidyl Hydrochloride Oral Solution USP is a synthetic antispasmodic drug It is designated chemically as α Cyclohexyl α phenyl 1 piperidinepropanol hydrochloride and its structural formula is as follows C 20 H 31 NO•HCl Trihexyphenidyl hydrochloride occurs as a white or creamy white almost odorless crystalline powder
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US20010046423A1 Know More Operating head for automatic machine tools of the type comprising a structure 2 which moves along a set of three Cartesian axes a first support 3 fitted to the said structure in such a way that it can rotate around a first axis C and a chuck unit 5 fitted to the said support wherein the said chuck unit 5 is interchangeable and projects from the said first
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PDF On Oct 24 2024 Talha N Jilani and others published Trihexyphenidyl Find read and cite all the research you need on ResearchGate
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National Center for Biotechnology Information 8600 Rockville Pike Bethesda MD 20894 USA Contact Policies FOIA HHS Vulnerability Disclosure National Library of Medicine National Institutes of Health Department of Health and Human Services
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Trihexyphenidyl exerts its effects by reducing the effects of the relative central cholinergic excess that occurs as a result of dopamine deficiency Indications and dose Parkinson s disease if used in combination with co careldopa or co beneldopa By mouth Adult
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Trihexyphenidyl Safety Data Sheet Safety Data Sheet in accordance with regulation EC No 1907/2024 as amended 04/04/2024 EN English 4/5 SECTION 11 Toxicological information Information on toxicological effects Acute toxicity Oral Harmful if swallowed Inhalation Harmful if inhaled Trihexyphenidyl LD50 oral rat 300 2024 mg/kg
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Trihexyphenidyl exerts its effects by reducing the effects of the relative central cholinergic excess that occurs as a result of dopamine deficiency Indications and dose Dystonia By mouth Child 3 months 17 years
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Dec 22 2021Trihexyphenidyl Description Trihexyphenidyl hydrochloride Tablets USP is a synthetic antispasmodic drug available in the following forms Tablets 2 mg and 5 mg It is designated chemically 1 Piperidinepropanol α cyclohexyl α phenyl hydrochloride The structural formula is represented below Trihexyphenidyl Hydrochloride Tablets USP 2 mg
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Trihexyphenidyl HCl is indicated as an adjunct in the treatment of all forms of parkinsonism postencephalitic arteriosclerotic and idiopathic It is often useful as adjuvant therapy when CONTRAINDICATIONS Trihexyphenidyl HCl is contraindicated in patients with hypersensitivity to trihexyphenidyl HCl or to any of the tablet ingredients
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Feb 27 2022Indications Trihexyphenidyl works as an anticholinergic used for the treatment of tremors spasms stiffness and weak muscle control seen in patients with Parkinson disease [1] It can also be useful for preventing or treating similar muscular conditions which are caused by certain central nervous system CNS drugs such as fluphenazine
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Trihexyphenidyl I Remember Very Little LegallyPrescribed Trihexyphenidyl Artane Experience Reports are the writings and opinions of the individual authors who submit them Some of the activities described are dangerous and/or illegal and none are recommended by Erowid
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Both Trihexyphenidyl and Ipratropium can cause antimuscarinic effects Levodopa Trihexyphenidyl decreases the absorption of Levodopa Manufacturer makes no recommendation Severity Moderate Evidence Theoretical Levomepromazine Both Trihexyphenidyl and Levomepromazine can cause antimuscarinic effects Lofepramine
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Trihexyphenidyl is used to treat symptoms of Parkinson s disease stiffness tremors spasms poor muscle control Trihexyphenidyl is also used to treat and prevent Parkinson like
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The clinical efficacy of the trihexyphenidyl was investigated in 100 patients with movement disorders The study group consisted of 54 women and 46 men Their ages ranged from 18 to 70 years and their duration of illness varied from a few months to 36 years Each patient had a videotape of the movements and a neurological examination before
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Description Trihexyphenidyl HCl is a tertiary amine antimuscarinic which exerts a direct inhibitory effect on the parasympathetic nervous system It also exhibits a direct spasmolytic action on smooth muscle weak mydriatic antisialagogue and cardiovagal blocking effects Onset W/in 1 hr Duration 6 12 hr Pharmacokinetics
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